John Cusack .... Craig Schwartz
Cameron Diaz .... Lotte Schwartz
Ned Bellamy .... Derek Mantini
Eric Weinstein .... Father at Puppet Show
Madison Lanc .... Daughter at Puppet Show
Octavia Spencer .... Woman in Elevator (as Octavia L. Spencer)
Mary Kay Place .... Floris
Orson Bean .... Dr. Lester
Catherine Keener .... Maxine
K.K. Dodds .... Wendy
Reginald C. Hayes .... Don (as Reggie Hayes)
Byrne Piven .... Captain Mertin
Judith Wetzell .... Tiny Woman
John Malkovich .... John Horatio Malkovich
Kevin Carroll .... Cab Driver